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Trial Search

Current Search Criteria:

Intervention: AT-527 (R07496998)

Found 11 matching trials

Drug-drug Interaction Study of Midazolam and AT-527 (R07496998)

PHASE1

Drug-drug interaction study of midazolam and AT-527 (R07496998)...

Status

Completed

Location

Atea Study Site

Start Date

2021-04-22

Trial ID

NCT04865445

Treatments Being Tested

AT-527 550 mg + midazolam AT-527 550 mg + midazolam

Bronchopulmonary PK of AT-527 (R07496998)

PHASE1

This study will assess the safety, tolerability and bronchopulmonary pharma...

Status

Completed

Location

Atea Study Site

Start Date

2021-04-25

Trial ID

NCT04877769

Treatments Being Tested

AT-527

Study to Evaluate the Effects of RO7496998 (AT-527) in Non-Hospitalized Adult and Adolescent Participants With Mild or Moderate COVID-19

PHASE3

This study will evaluate the efficacy, safety, antiviral activity, and phar...

Status

Terminated

Location

Instituto Ave Pulmo

Start Date

2021-04-28

Trial ID

NCT04889040

Treatments Being Tested

RO7496998 Placebo

Study of AT-527 in Healthy Subjects (R07496998)

PHASE1

This study will assess the safety, tolerability and pharmacokinetics (PK) o...

Status

Completed

Location

Atea Study Site

Start Date

2020-11-02

Trial ID

NCT04711187

Treatments Being Tested

AT-527 Formulation 1 Placebo Comparator AT-527 Formulation 2

Drug-drug Interaction Study of Rosuvastatin and AT-527 (R07496998)

PHASE1

Drug-drug interaction study of rosuvastatin and AT-527 (R07496998)...

Status

Completed

Location

Atea Study Site

Start Date

2021-11-16

Trial ID

NCT05154123

Treatments Being Tested

Drug: AT-527 + rosuvastatin AT-527 + rosuvastatin

Effect of Cyclosporine on the Pharmacokinetics (PK) of AT-527 (R07496998)

PHASE1

This study will determine the effect of cyclosporine on the PK of AT-527 (R...

Status

Completed

Location

Atea Study Site

Start Date

2021-04-18

Trial ID

NCT04849299

Treatments Being Tested

AT-527 550 mg + cyclosporine AT-527 550 mg + cyclosporine

A Six-Month Follow-Up Study of Participants With Coronavirus Disease 2019 (COVID-19) Previously Enrolled in a RO7496998 (AT-527) Study

N/A

This study will evaluate the long-term sequelae of COVID-19 in patients dia...

Status

Terminated

Location

Instituto Ave Pulmo

Start Date

2021-06-15

Trial ID

NCT05059080

Mass Balance Study of AT-527 in Healthy Adult Male Subjects (R07496998)

PHASE1

Mass balance study of AT-527 in Healthy Male Subjects....

Status

Completed

Location

Atea Study Site

Start Date

2021-07-28

Trial ID

NCT05004415

Treatments Being Tested

AT-527 (R07496998)

Effect of Carbamazepine on the Pharmacokinetics (PK) of AT-527

PHASE1

This study will determine the effect of carbamazepine on the PK of AT-527 (...

Status

Completed

Location

Atea Study Site

Start Date

2021-03-01

Trial ID

NCT04784000

Treatments Being Tested

Period 1: AT-527 550 mg Period 2: carbamazepine Period 3: AT-527 550 mg + carbamazepine Period 3: AT-527 1100 mg + carbamazepine

Study to Evaluate the Effects of AT-527 in Non-Hospitalized Adult Patients With Mild or Moderate COVID-19

PHASE2

This randomized study evaluates the antiviral activity, safety, efficacy an...

Status

Completed

Location

Hamilton Medical Research Group

Start Date

2021-02-03

Trial ID

NCT04709835

Treatments Being Tested

AT-527 Placebo

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